But usually when those problems occur, they occur within six weeks of a dose. But again, we need to be humble, keep our eyes open and look what happens as we vaccinate hundreds and hundreds of millions of people to make sure that there's not an additional problem. And now that the vaccine has been given to more than 10 million people, I think you can say with some confidence that there doesn't appear to be right now a very rare, serious side effect that would be something that would cause a long-term problem. So I think in those preapproval studies where the vaccines have been tested in tens of thousands of people, you could say with confidence that there wasn't at least a relatively uncommon, serious side effect. So, although some of those effects are long term like polio or narcolepsy, they're still picked up within six weeks. That's why it is that the FDA, the Food and Drug Administration, insisted that each of these vaccines be studied for at least two months after the last dose, knowing that there's not been a serious side effect in history that hasn't occurred within weeks of getting the dose, within six weeks of getting the dose. Some dosage forms listed on this page may not apply to the brand name Pfizer-BioNTech COVID-19 Vaccine. The good news about these terrible side effects is that they all occur within six weeks of a dose. Note: This document contains side effect information about sars-cov-2 mrna (tozinameran) vaccine. And, measles-containing vaccine can cause a lowering of the platelet count, which can cause these sort of like broken blood vessels called petechiae again, occurred in maybe 1 in 30,000 people - rare but real. There was a squalene adjuvanted influenza vaccine that was used in Europe that was also a very rare cause of something called narcolepsy, which is a permanent disorder of wakefulness. Yellow fever vaccine was a rare cause of something that had the fancy name viscerotropic disease, which is really basically a form of yellow fever again, occurred in about 1 in a million people it was rare, but it was real. So for example, vaccines like the oral polio vaccine was a rare cause of polio it occurred in maybe 1 per 2.4 million people, but it was real. Well, vaccines like any medical product that have a positive effect can have a negative effect, and that's true here too. It is January 2021, and now in the midst of this pandemic, and now with the advent of two new vaccines, so-called messenger RNA vaccines to prevent SARS-CoV-2, people ask the reasonable question: Since this is a new strategy, a new way to make a vaccine, what are the long-term effects? How are we going to know about the long-term effects? My name is Paul Offit from the Vaccine Education Center. These antibodies trigger inflammation that produces the blisters and itching of bullous pemphigoid.What are the long-term side effects of COVID-19 vaccine? "In bullous pemphigoid, the immune system produces antibodies to the fibers that connect the outer layer of skin (epidermis) and the next layer of skin (dermis). For reasons that are not clear, the body may develop an antibody to a particular tissue in your body. The health body continues: "Your body's immune system normally produces antibodies to fight bacteria, viruses or other potentially harmful foreign substances. "The blisters occur because of a malfunction in your immune system," explains the Mayo Clinic. Small blisters or sores in the mouth or other mucous membranes (benign mucous membrane pemphigoid).Skin around the blisters that is normal, reddish or darker than normal.Large blisters that don't easily rupture when touched, often along creases or folds in the skin.Itching skin, weeks or months before blisters form. The signs and symptoms of bullous pemphigoid may include: Bullous pemphigoid blisters develop on areas of skin that often flex - such as the lower abdomen, upper thighs or armpits, explains the Mayo Clinic.
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